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Osamu Shimomura Selected Research

rBC2LCN lectin

8/2023Novel positron emission tomography imaging targeting cell surface glycans for pancreatic cancer: 18 F-labeled rBC2LCN lectin.
9/2021Carcinoembryonic antigen as a specific glycoprotein ligand of rBC2LCN lectin on pancreatic ductal adenocarcinoma cells.
12/2020Lectin drug conjugate therapy for colorectal cancer.
1/2020Novel Pancreatic Cancer Therapy Targeting Cell Surface Glycans by Liposomes Modified with rBC2LCN Lectin.

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Osamu Shimomura Research Topics

Disease

15Neoplasms (Cancer)
01/2024 - 12/2006
9Pancreatic Neoplasms (Pancreatic Cancer)
01/2024 - 04/2016
6Adenocarcinoma
01/2024 - 06/2021
4Pancreatic Fistula (Pancreatic Fistulas)
07/2022 - 08/2015
3Hyperthermia
07/2023 - 04/2016
3Neoplasm Metastasis (Metastasis)
07/2022 - 08/2018
3Stomach Neoplasms (Stomach Cancer)
07/2022 - 10/2020
3Hepatocellular Carcinoma (Hepatoma)
01/2022 - 11/2018
2Abdominal Pain (Pain, Abdominal)
05/2024 - 08/2021
2Wounds and Injuries (Trauma)
01/2024 - 08/2021
2Diarrhea
12/2023 - 11/2023
2Esophageal Neoplasms (Esophageal Cancer)
12/2022 - 12/2021
2Breast Neoplasms (Breast Cancer)
01/2022 - 01/2021
1Mesenteric Ischemia
05/2024
1Ischemia
05/2024
1Hypoxia (Hypoxemia)
01/2024
1Bites and Stings (Sting)
01/2024
1Surgical Wound Infection
01/2024
1Carcinoma (Carcinomatosis)
06/2023
1Chylothorax
12/2022
1Aneurysm (Aneurysms)
06/2022
1Liver Failure
01/2022
1Signet Ring Cell Carcinoma
01/2022
1Esophageal Squamous Cell Carcinoma
10/2021
1Short Bowel Syndrome
08/2021
1Thrombosis (Thrombus)
03/2021
1Colorectal Neoplasms (Colorectal Cancer)
12/2020
1Intestinal Fistula
03/2020

Drug/Important Bio-Agent (IBA)

9Polysaccharides (Glycans)IBA
01/2024 - 01/2018
7LectinsIBA
01/2024 - 01/2018
5Proteins (Proteins, Gene)FDA Link
01/2024 - 01/2018
4rBC2LCN lectinIBA
08/2023 - 01/2020
3Protons (Proton)IBA
07/2023 - 06/2021
3Drug CarriersIBA
12/2020 - 01/2018
2GemcitabineFDA Link
07/2023 - 06/2021
2Member 1 Subfamily B ATP Binding Cassette TransporterIBA
01/2022 - 01/2021
2Peptide Transporter 1IBA
01/2022 - 01/2021
1Fluorouracil (Carac)FDA LinkGeneric
01/2024
1ErbB Receptors (EGF Receptor)IBA
12/2023
1osimertinibIBA
12/2023
1Tyrosine Kinase InhibitorsIBA
12/2023
1AfatinibIBA
12/2023
1Opioid Analgesics (Opioids)IBA
11/2023
1Fluorine-18IBA
08/2023
1130-nm albumin-bound paclitaxelIBA
07/2023
1tyramine-deoxysorbitolIBA
12/2022
1AmylasesFDA Link
07/2022
1UridineIBA
01/2022
1EnzymesIBA
01/2022
1Therapeutic UsesIBA
01/2022
1AlbuminsIBA
01/2022
1Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
01/2022
1BilirubinIBA
01/2022
1Cytochrome P-450 CYP2C9IBA
01/2022
1Carboxylesterase (Hydrolase S)IBA
01/2022
1ExotoxinsIBA
01/2022
1VimentinIBA
11/2021
1Calmodulin-Binding Proteins (Caldesmon)IBA
11/2021
1DesminIBA
11/2021
1Factor VIII (Coagulation Factor VIII)IBA
11/2021
1Inhibins (Inhibin)IBA
11/2021
1Keratins (Keratin)IBA
11/2021
1MART-1 AntigenIBA
11/2021
1TrisaccharidesIBA
09/2021
1Carrier Proteins (Binding Protein)IBA
09/2021
1Glycoproteins (Glycoprotein)IBA
09/2021
1Carcinoembryonic AntigenIBA
09/2021
1LigandsIBA
09/2021
1lenvatinibIBA
03/2021
1NucleosidesIBA
01/2021
1Methotrexate (Mexate)FDA LinkGeneric
01/2021
1Cefadroxil (Duricef)FDA LinkGeneric
01/2021
1Ribavirin (Virazole)FDA LinkGeneric
01/2021
1EpitopesIBA
01/2021
1Proton-Coupled Folate TransporterIBA
01/2021
1tegafur-gimeracil-oteracilIBA
10/2020

Therapy/Procedure

9Therapeutics
05/2024 - 04/2016
4Pancreaticoduodenectomy
11/2023 - 08/2015
4Hepatectomy
01/2022 - 08/2018
3Drug Therapy (Chemotherapy)
07/2023 - 01/2007
3Esophagectomy
06/2023 - 12/2021
3Pancreatectomy
06/2022 - 08/2018
2Proton Therapy
07/2023 - 10/2021
2Length of Stay
07/2022 - 08/2015
2Gastrectomy
07/2022 - 10/2020
2Chemoradiotherapy
10/2021 - 06/2021
1Sutures (Suture)
01/2024
1Suture Techniques
01/2024
1Phototherapy (Light Therapy)
01/2023
1Ligation
12/2022
1Minimally Invasive Surgical Procedures
01/2022
1Operative Time
01/2022
1Neoadjuvant Therapy
10/2021
1Parenteral Nutrition
08/2021
1Laparotomy
08/2021
1Skin Transplantation (Skin Grafting)
08/2021
1Total Parenteral Nutrition
08/2021
1Adjuvant Chemotherapy
10/2020
1Conversion to Open Surgery
03/2020
1Enema (Enemas)
03/2020